Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50298040
((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...)Show SMILES CN1CC[C@@H](C1)N(CC1CCCCC1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H26ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h7-8,11,15,18H,2-6,9-10,13-14H2,1H3/t18-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay |
Bioorg Med Chem Lett 19: 4777-80 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50298040
((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...)Show SMILES CN1CC[C@@H](C1)N(CC1CCCCC1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H26ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h7-8,11,15,18H,2-6,9-10,13-14H2,1H3/t18-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay |
Bioorg Med Chem Lett 19: 4777-80 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG |
More data for this Ligand-Target Pair | |