Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1F receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1F receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1F receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1A receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1A receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50156402
(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...)Show SMILES CN1CCC(CC1)C1CNc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12,14,19,23H,8-11,13H2,1H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 14: 6011-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.079
BindingDB Entry DOI: 10.7270/Q23J3CFK |
More data for this
Ligand-Target Pair | |