Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human)) | BDBM50130436
(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(C)c3)nc12 Show InChI InChI=1S/C21H24N4O/c1-14-4-3-5-16(12-14)21(26)24-19-7-6-18-20(23-19)17(13-22-18)15-8-10-25(2)11-9-15/h3-7,12-13,15,22H,8-11H2,1-2H3,(H,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50130436
(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(C)c3)nc12 Show InChI InChI=1S/C21H24N4O/c1-14-4-3-5-16(12-14)21(26)24-19-7-6-18-20(23-19)17(13-22-18)15-8-10-25(2)11-9-15/h3-7,12-13,15,22H,8-11H2,1-2H3,(H,23,24,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50130436
(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(C)c3)nc12 Show InChI InChI=1S/C21H24N4O/c1-14-4-3-5-16(12-14)21(26)24-19-7-6-18-20(23-19)17(13-22-18)15-8-10-25(2)11-9-15/h3-7,12-13,15,22H,8-11H2,1-2H3,(H,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50130436
(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(C)c3)nc12 Show InChI InChI=1S/C21H24N4O/c1-14-4-3-5-16(12-14)21(26)24-19-7-6-18-20(23-19)17(13-22-18)15-8-10-25(2)11-9-15/h3-7,12-13,15,22H,8-11H2,1-2H3,(H,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |