Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM167664
(US9073922, 151 | US9796708, Example 151)Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCCN2CCCC2=O)n1 Show InChI InChI=1S/C24H30N6O/c1-29-13-8-17(9-14-29)21-16-19-18(7-10-26-24(19)28-21)20-4-2-5-22(27-20)25-11-15-30-12-3-6-23(30)31/h2,4-5,7,10,16-17H,3,6,8-9,11-15H2,1H3,(H,25,27)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... |
US Patent US9796708 (2017)
BindingDB Entry DOI: 10.7270/Q2WD42P4 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM167664
(US9073922, 151 | US9796708, Example 151)Show SMILES CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cccc(NCCN2CCCC2=O)n1 Show InChI InChI=1S/C24H30N6O/c1-29-13-8-17(9-14-29)21-16-19-18(7-10-26-24(19)28-21)20-4-2-5-22(27-20)25-11-15-30-12-3-6-23(30)31/h2,4-5,7,10,16-17H,3,6,8-9,11-15H2,1H3,(H,25,27)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc.
US Patent
| Assay Description
CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... |
US Patent US9073922 (2015)
BindingDB Entry DOI: 10.7270/Q2CJ8C78 |
More data for this
Ligand-Target Pair | |