Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM185384
(US9156845, 28)Show SMILES CN1CCC2(CC1)CN(CCO2)c1ncnc2[nH]cc(-c3cccc(c3)C#N)c12 Show InChI InChI=1S/C22H24N6O/c1-27-7-5-22(6-8-27)14-28(9-10-29-22)21-19-18(13-24-20(19)25-15-26-21)17-4-2-3-16(11-17)12-23/h2-4,11,13,15H,5-10,14H2,1H3,(H,24,25,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pfizer Inc.
US Patent
| Assay Description
LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu... |
US Patent US9156845 (2015)
BindingDB Entry DOI: 10.7270/Q2DB80MW |
More data for this
Ligand-Target Pair | |
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]
(Homo sapiens (Human)) | BDBM185384
(US9156845, 28)Show SMILES CN1CCC2(CC1)CN(CCO2)c1ncnc2[nH]cc(-c3cccc(c3)C#N)c12 Show InChI InChI=1S/C22H24N6O/c1-27-7-5-22(6-8-27)14-28(9-10-29-22)21-19-18(13-24-20(19)25-15-26-21)17-4-2-3-16(11-17)12-23/h2-4,11,13,15H,5-10,14H2,1H3,(H,24,25,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 201 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pfizer Inc.
US Patent
| Assay Description
LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu... |
US Patent US9156845 (2015)
BindingDB Entry DOI: 10.7270/Q2DB80MW |
More data for this
Ligand-Target Pair | |