Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463449
(3-(4-Methyl-1,4-diazepan-1-yl)-2-phenylquinoxaline...)Show SMILES CN1CCCN(CC1)c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H22N4O2/c1-24-10-5-11-25(13-12-24)20-19(15-6-3-2-4-7-15)22-17-9-8-16(21(26)27)14-18(17)23-20/h2-4,6-9,14H,5,10-13H2,1H3,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description
Purified hPASK from insect cells (0.02 μg) is added to a 50 μL reaction mix containing 40 mM HEPES (pH 7.0), 100 mM KCl, 5 mM MgCl2, 1 mM D... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this
Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463449
(3-(4-Methyl-1,4-diazepan-1-yl)-2-phenylquinoxaline...)Show SMILES CN1CCCN(CC1)c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H22N4O2/c1-24-10-5-11-25(13-12-24)20-19(15-6-3-2-4-7-15)22-17-9-8-16(21(26)27)14-18(17)23-20/h2-4,6-9,14H,5,10-13H2,1H3,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description
Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this
Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463449
(3-(4-Methyl-1,4-diazepan-1-yl)-2-phenylquinoxaline...)Show SMILES CN1CCCN(CC1)c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H22N4O2/c1-24-10-5-11-25(13-12-24)20-19(15-6-3-2-4-7-15)22-17-9-8-16(21(26)27)14-18(17)23-20/h2-4,6-9,14H,5,10-13H2,1H3,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaining in sol... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this
Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase [879-1323]
(Homo sapiens (Human)) | BDBM463449
(3-(4-Methyl-1,4-diazepan-1-yl)-2-phenylquinoxaline...)Show SMILES CN1CCCN(CC1)c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H22N4O2/c1-24-10-5-11-25(13-12-24)20-19(15-6-3-2-4-7-15)22-17-9-8-16(21(26)27)14-18(17)23-20/h2-4,6-9,14H,5,10-13H2,1H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this
Ligand-Target Pair | |