Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 512.6 BDBM515454

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM515454 (US11098061, Compound V-15) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM515454 (US11098061, Compound V-15) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW
					More data for this Ligand-Target Pair