Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Caspase-3
(Homo sapiens (Human)) | BDBM50002736
(CHEMBL3233633)Show InChI InChI=1S/C19H20N4O2S/c1-21-10-12-22(13-11-21)15-8-6-14(7-9-15)20-19(25)23-18(24)16-4-2-3-5-17(16)26-23/h2-9H,10-13H2,1H3,(H,20,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant caspase-3 using Ac-LDEVD-AMC as substrate after 10 mins by fluorescence assay |
Bioorg Med Chem 22: 2416-26 (2014)
Article DOI: 10.1016/j.bmc.2014.03.002 BindingDB Entry DOI: 10.7270/Q2J38V2W |
More data for this Ligand-Target Pair | |
Caspase-7
(Homo sapiens (Human)) | BDBM50002736
(CHEMBL3233633)Show InChI InChI=1S/C19H20N4O2S/c1-21-10-12-22(13-11-21)15-8-6-14(7-9-15)20-19(25)23-18(24)16-4-2-3-5-17(16)26-23/h2-9H,10-13H2,1H3,(H,20,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate after 10 mins by fluorescence assay |
Bioorg Med Chem 22: 2416-26 (2014)
Article DOI: 10.1016/j.bmc.2014.03.002 BindingDB Entry DOI: 10.7270/Q2J38V2W |
More data for this Ligand-Target Pair | |