Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase D1
(Homo sapiens (Human)) | BDBM50324292
(CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...)Show SMILES CN1CCN(CC1)c1nc(cc2cnccc12)-c1ccnc(NC2CCCCC2)c1 Show InChI InChI=1S/C24H30N6/c1-29-11-13-30(14-12-29)24-21-8-9-25-17-19(21)15-22(28-24)18-7-10-26-23(16-18)27-20-5-3-2-4-6-20/h7-10,15-17,20H,2-6,11-14H2,1H3,(H,26,27) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of PKD1 by TR-FRET assay |
J Med Chem 53: 5400-21 (2010)
Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase D1
(Homo sapiens (Human)) | BDBM50324292
(CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...)Show SMILES CN1CCN(CC1)c1nc(cc2cnccc12)-c1ccnc(NC2CCCCC2)c1 Show InChI InChI=1S/C24H30N6/c1-29-11-13-30(14-12-29)24-21-8-9-25-17-19(21)15-22(28-24)18-7-10-26-23(16-18)27-20-5-3-2-4-6-20/h7-10,15-17,20H,2-6,11-14H2,1H3,(H,26,27) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of PKD1 assessed as HDAC5 neuclear export |
J Med Chem 53: 5400-21 (2010)
Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 |
More data for this Ligand-Target Pair | |