Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 465.4 BDBM487790

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487790 (N-(2-methyl-1-oxo-1,2,3,4- tetrahydroisoquinolin-7...) Show SMILES CN1CCc2ccc(NC(=O)c3cnn(c3C(F)(F)F)-c3cccc4ncccc34)cc2C1=O Show InChI InChI=1S/C24H18F3N5O2/c1-31-11-9-14-7-8-15(12-17(14)23(31)34)30-22(33)18-13-29-32(21(18)24(25,26)27)20-6-2-5-19-16(20)4-3-10-28-19/h2-8,10,12-13H,9,11H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
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