Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas
Curated by ChEMBL
| Assay Description Compounds were tested for inhibition against human liver Monoamine oxidase B (competitive inhibition was observed) |
J Med Chem 33: 147-52 (1990)
BindingDB Entry DOI: 10.7270/Q26110X9 |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptor |
Bioorg Med Chem Lett 9: 481-6 (1999)
BindingDB Entry DOI: 10.7270/Q26Q20F9 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT) |
Bioorg Med Chem Lett 9: 481-6 (1999)
BindingDB Entry DOI: 10.7270/Q26Q20F9 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas
Curated by ChEMBL
| Assay Description Inhibition of human placental Monoamine oxidase A (competitive inhibition was observed) |
J Med Chem 33: 147-52 (1990)
BindingDB Entry DOI: 10.7270/Q26110X9 |
More data for this Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(RAT) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle& Co.
Curated by ChEMBL
| Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor |
J Med Chem 32: 1242-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CR5TXJ |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50014651
(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)Show InChI InChI=1S/C10H13N/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5H,6-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle& Co.
Curated by ChEMBL
| Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor |
J Med Chem 32: 1242-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CR5TXJ |
More data for this Ligand-Target Pair | |