Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM325738
((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)Show SMILES CNC(=O)CC1CCc2cncc(c12)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C18H16F4N2O/c1-23-16(25)7-11-2-3-12-8-24-9-13(17(11)12)10-4-5-14(15(19)6-10)18(20,21)22/h4-6,8-9,11H,2-3,7H2,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 113 | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9636338 (2017)
BindingDB Entry DOI: 10.7270/Q2988938 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM325738
((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)Show SMILES CNC(=O)CC1CCc2cncc(c12)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C18H16F4N2O/c1-23-16(25)7-11-2-3-12-8-24-9-13(17(11)12)10-4-5-14(15(19)6-10)18(20,21)22/h4-6,8-9,11H,2-3,7H2,1H3,(H,23,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9636338 (2017)
BindingDB Entry DOI: 10.7270/Q2988938 |
More data for this Ligand-Target Pair | |