Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 353.4 BDBM50546798

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM50546798 (CHEMBL4779026) Show SMILES CNC(=O)CCS(=O)(=O)N1CCN(CC1)c1ccc2nncn2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair