Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50349666
(CHEMBL1809031)Show SMILES CNC(=O)N1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCCC1 |r,c:7| Show InChI InChI=1S/C21H24N4O2/c1-22-21(27)25-12-14(20(26)24-7-2-3-8-24)9-16-15-5-4-6-17-19(15)13(11-23-17)10-18(16)25/h4-6,9,11,14,18,23H,2-3,7-8,10,12H2,1H3,(H,22,27)/t14-,18-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 4745-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.070
BindingDB Entry DOI: 10.7270/Q2VM4CN5 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50349666
(CHEMBL1809031)Show SMILES CNC(=O)N1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCCC1 |r,c:7| Show InChI InChI=1S/C21H24N4O2/c1-22-21(27)25-12-14(20(26)24-7-2-3-8-24)9-16-15-5-4-6-17-19(15)13(11-23-17)10-18(16)25/h4-6,9,11,14,18,23H,2-3,7-8,10,12H2,1H3,(H,22,27)/t14-,18-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Displacement of radiolabeled CXCL11 from human CXCR3 expressed in CHO cells by scintillation proximity assay |
Bioorg Med Chem Lett 21: 4745-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.070
BindingDB Entry DOI: 10.7270/Q2VM4CN5 |
More data for this
Ligand-Target Pair | |