Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317477
(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)Show SMILES CNC(=O)c1cc(OC)c(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)cc1F Show InChI InChI=1S/C28H27FN6O4/c1-14-32-20-9-8-15(10-23(20)38-14)18-13-31-25-24(18)27(39-16-6-4-5-7-16)35-28(34-25)33-21-12-19(29)17(26(36)30-2)11-22(21)37-3/h8-13,16H,4-7H2,1-3H3,(H,30,36)(H2,31,33,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.06 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317477
(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)Show SMILES CNC(=O)c1cc(OC)c(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)cc1F Show InChI InChI=1S/C28H27FN6O4/c1-14-32-20-9-8-15(10-23(20)38-14)18-13-31-25-24(18)27(39-16-6-4-5-7-16)35-28(34-25)33-21-12-19(29)17(26(36)30-2)11-22(21)37-3/h8-13,16H,4-7H2,1-3H3,(H,30,36)(H2,31,33,34,35) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317477
(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)Show SMILES CNC(=O)c1cc(OC)c(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)cc1F Show InChI InChI=1S/C28H27FN6O4/c1-14-32-20-9-8-15(10-23(20)38-14)18-13-31-25-24(18)27(39-16-6-4-5-7-16)35-28(34-25)33-21-12-19(29)17(26(36)30-2)11-22(21)37-3/h8-13,16H,4-7H2,1-3H3,(H,30,36)(H2,31,33,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |