Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitotic checkpoint serine/threonine-protein kinase BUB1
(Homo sapiens (Human)) | BDBM379090
(Preparation of formic acid-3-chloro-4-({3-[5-metho...)Show SMILES CNC(=O)c1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C26H22ClN7O2/c1-28-26(35)16-7-8-17(20(27)13-16)15-34-21-6-4-3-5-19(21)23(33-34)25-30-14-22(36-2)24(32-25)31-18-9-11-29-12-10-18/h3-14H,15H2,1-2H3,(H,28,35)(H,29,30,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical
| Assay Description
Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE... |
J Med Chem 51: 4150-69 (2008)
BindingDB Entry DOI: 10.7270/Q2RV0R1M |
More data for this
Ligand-Target Pair | |
Mitotic checkpoint serine/threonine-protein kinase BUB1
(Homo sapiens (Human)) | BDBM379090
(Preparation of formic acid-3-chloro-4-({3-[5-metho...)Show SMILES CNC(=O)c1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C26H22ClN7O2/c1-28-26(35)16-7-8-17(20(27)13-16)15-34-21-6-4-3-5-19(21)23(33-34)25-30-14-22(36-2)24(32-25)31-18-9-11-29-12-10-18/h3-14H,15H2,1-2H3,(H,28,35)(H,29,30,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical
| Assay Description
Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE... |
J Med Chem 51: 4150-69 (2008)
BindingDB Entry DOI: 10.7270/Q2RV0R1M |
More data for this
Ligand-Target Pair | |