Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317456
(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(c1)C(C)C Show InChI InChI=1S/C28H31N5O3/c1-16(2)21-14-18(26(35)29-3)10-13-23(21)31-28-32-25-24(27(33-28)36-20-6-4-5-7-20)22(15-30-25)17-8-11-19(34)12-9-17/h8-16,20,34H,4-7H2,1-3H3,(H,29,35)(H2,30,31,32,33) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 34.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317456
(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(c1)C(C)C Show InChI InChI=1S/C28H31N5O3/c1-16(2)21-14-18(26(35)29-3)10-13-23(21)31-28-32-25-24(27(33-28)36-20-6-4-5-7-20)22(15-30-25)17-8-11-19(34)12-9-17/h8-16,20,34H,4-7H2,1-3H3,(H,29,35)(H2,30,31,32,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 299 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |