Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317484
(3-chloro-4-(4-(cyclopentyloxy)-5- (2-methylbenzo[d...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O3/c1-14-31-21-10-7-15(12-22(21)36-14)18-13-30-24-23(18)26(37-17-5-3-4-6-17)34-27(33-24)32-20-9-8-16(11-19(20)28)25(35)29-2/h7-13,17H,3-6H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 11.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317484
(3-chloro-4-(4-(cyclopentyloxy)-5- (2-methylbenzo[d...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O3/c1-14-31-21-10-7-15(12-22(21)36-14)18-13-30-24-23(18)26(37-17-5-3-4-6-17)34-27(33-24)32-20-9-8-16(11-19(20)28)25(35)29-2/h7-13,17H,3-6H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317484
(3-chloro-4-(4-(cyclopentyloxy)-5- (2-methylbenzo[d...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O3/c1-14-31-21-10-7-15(12-22(21)36-14)18-13-30-24-23(18)26(37-17-5-3-4-6-17)34-27(33-24)32-20-9-8-16(11-19(20)28)25(35)29-2/h7-13,17H,3-6H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 505 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |