Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317472
(N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(C)c1 Show InChI InChI=1S/C28H28N6O4/c1-15-12-18(26(35)29-3)5-6-21(15)32-28-33-25-24(27(34-28)38-19-8-10-36-11-9-19)20(14-30-25)17-4-7-22-23(13-17)37-16(2)31-22/h4-7,12-14,19H,8-11H2,1-3H3,(H,29,35)(H2,30,32,33,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317472
(N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(C)c1 Show InChI InChI=1S/C28H28N6O4/c1-15-12-18(26(35)29-3)5-6-21(15)32-28-33-25-24(27(34-28)38-19-8-10-36-11-9-19)20(14-30-25)17-4-7-22-23(13-17)37-16(2)31-22/h4-7,12-14,19H,8-11H2,1-3H3,(H,29,35)(H2,30,32,33,34) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 40.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317472
(N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(C)c1 Show InChI InChI=1S/C28H28N6O4/c1-15-12-18(26(35)29-3)5-6-21(15)32-28-33-25-24(27(34-28)38-19-8-10-36-11-9-19)20(14-30-25)17-4-7-22-23(13-17)37-16(2)31-22/h4-7,12-14,19H,8-11H2,1-3H3,(H,29,35)(H2,30,32,33,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description
The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this
Ligand-Target Pair | |