Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317475
(3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-y...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(c1)C#N Show InChI InChI=1S/C28H25N7O4/c1-15-32-22-6-3-16(12-23(22)38-15)20-14-31-25-24(20)27(39-19-7-9-37-10-8-19)35-28(34-25)33-21-5-4-17(26(36)30-2)11-18(21)13-29/h3-6,11-12,14,19H,7-10H2,1-2H3,(H,30,36)(H2,31,33,34,35) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.47 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317475
(3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-y...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(c1)C#N Show InChI InChI=1S/C28H25N7O4/c1-15-32-22-6-3-16(12-23(22)38-15)20-14-31-25-24(20)27(39-19-7-9-37-10-8-19)35-28(34-25)33-21-5-4-17(26(36)30-2)11-18(21)13-29/h3-6,11-12,14,19H,7-10H2,1-2H3,(H,30,36)(H2,31,33,34,35) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 2.32 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317475
(3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-y...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(c1)C#N Show InChI InChI=1S/C28H25N7O4/c1-15-32-22-6-3-16(12-23(22)38-15)20-14-31-25-24(20)27(39-19-7-9-37-10-8-19)35-28(34-25)33-21-5-4-17(26(36)30-2)11-18(21)13-29/h3-6,11-12,14,19H,7-10H2,1-2H3,(H,30,36)(H2,31,33,34,35) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 82.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |