Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317485
(3-chloro-N-methyl-4-(5-(1- methyl-1H-pyrazol-4-yl)...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2cnn(C)c2)c(Cl)c1 Show InChI InChI=1S/C23H24ClN7O3/c1-25-21(32)13-3-4-18(17(24)9-13)28-23-29-20-19(16(11-26-20)14-10-27-31(2)12-14)22(30-23)34-15-5-7-33-8-6-15/h3-4,9-12,15H,5-8H2,1-2H3,(H,25,32)(H2,26,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317485
(3-chloro-N-methyl-4-(5-(1- methyl-1H-pyrazol-4-yl)...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2cnn(C)c2)c(Cl)c1 Show InChI InChI=1S/C23H24ClN7O3/c1-25-21(32)13-3-4-18(17(24)9-13)28-23-29-20-19(16(11-26-20)14-10-27-31(2)12-14)22(30-23)34-15-5-7-33-8-6-15/h3-4,9-12,15H,5-8H2,1-2H3,(H,25,32)(H2,26,28,29,30) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3.29 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317485
(3-chloro-N-methyl-4-(5-(1- methyl-1H-pyrazol-4-yl)...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2cnn(C)c2)c(Cl)c1 Show InChI InChI=1S/C23H24ClN7O3/c1-25-21(32)13-3-4-18(17(24)9-13)28-23-29-20-19(16(11-26-20)14-10-27-31(2)12-14)22(30-23)34-15-5-7-33-8-6-15/h3-4,9-12,15H,5-8H2,1-2H3,(H,25,32)(H2,26,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 97.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |