Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245619
(US9428508, 74)Show SMILES CNC(=O)c1cccc(Nc2nc3NCCc3c(Nc3ccccc3S(=O)(=O)NC(C)C)n2)c1 Show InChI InChI=1S/C23H27N7O3S/c1-14(2)30-34(32,33)19-10-5-4-9-18(19)27-21-17-11-12-25-20(17)28-23(29-21)26-16-8-6-7-15(13-16)22(31)24-3/h4-10,13-14,30H,11-12H2,1-3H3,(H,24,31)(H3,25,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245619
(US9428508, 74)Show SMILES CNC(=O)c1cccc(Nc2nc3NCCc3c(Nc3ccccc3S(=O)(=O)NC(C)C)n2)c1 Show InChI InChI=1S/C23H27N7O3S/c1-14(2)30-34(32,33)19-10-5-4-9-18(19)27-21-17-11-12-25-20(17)28-23(29-21)26-16-8-6-7-15(13-16)22(31)24-3/h4-10,13-14,30H,11-12H2,1-3H3,(H,24,31)(H3,25,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |