Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245560
(US9428508, 14)Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2CO)N2CCOCC2)nc2NCCc12 Show InChI InChI=1S/C25H29N7O3/c1-26-24(34)18-4-2-3-5-21(18)28-23-19-8-9-27-22(19)30-25(31-23)29-20-7-6-17(14-16(20)15-33)32-10-12-35-13-11-32/h2-7,14,33H,8-13,15H2,1H3,(H,26,34)(H3,27,28,29,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245560
(US9428508, 14)Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2CO)N2CCOCC2)nc2NCCc12 Show InChI InChI=1S/C25H29N7O3/c1-26-24(34)18-4-2-3-5-21(18)28-23-19-8-9-27-22(19)30-25(31-23)29-20-7-6-17(14-16(20)15-33)32-10-12-35-13-11-32/h2-7,14,33H,8-13,15H2,1H3,(H,26,34)(H3,27,28,29,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |