Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245567
(US9428508, 22)Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cccc3n(CCCN4CCOCC4)ccc23)nc2NCCc12 Show InChI InChI=1S/C29H34N8O2/c1-30-28(38)21-6-2-3-7-24(21)32-27-22-10-12-31-26(22)34-29(35-27)33-23-8-4-9-25-20(23)11-15-37(25)14-5-13-36-16-18-39-19-17-36/h2-4,6-9,11,15H,5,10,12-14,16-19H2,1H3,(H,30,38)(H3,31,32,33,34,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245567
(US9428508, 22)Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cccc3n(CCCN4CCOCC4)ccc23)nc2NCCc12 Show InChI InChI=1S/C29H34N8O2/c1-30-28(38)21-6-2-3-7-24(21)32-27-22-10-12-31-26(22)34-29(35-27)33-23-8-4-9-25-20(23)11-15-37(25)14-5-13-36-16-18-39-19-17-36/h2-4,6-9,11,15H,5,10,12-14,16-19H2,1H3,(H,30,38)(H3,31,32,33,34,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |