Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50337212
(5-chloro-6-((3S)-4-(1-(1-(4-chlorophenyl)ethyl)pip...)Show SMILES CNC(=O)c1cnc(N2CCN([C@@H](C)C2)C2CCN(CC2)C(C)c2ccc(Cl)cc2)c(Cl)c1 |r| Show InChI InChI=1S/C25H33Cl2N5O/c1-17-16-31(24-23(27)14-20(15-29-24)25(33)28-3)12-13-32(17)22-8-10-30(11-9-22)18(2)19-4-6-21(26)7-5-19/h4-7,14-15,17-18,22H,8-13,16H2,1-3H3,(H,28,33)/t17-,18?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 |
Bioorg Med Chem Lett 21: 1527-31 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.114 BindingDB Entry DOI: 10.7270/Q2CZ37FJ |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50337212
(5-chloro-6-((3S)-4-(1-(1-(4-chlorophenyl)ethyl)pip...)Show SMILES CNC(=O)c1cnc(N2CCN([C@@H](C)C2)C2CCN(CC2)C(C)c2ccc(Cl)cc2)c(Cl)c1 |r| Show InChI InChI=1S/C25H33Cl2N5O/c1-17-16-31(24-23(27)14-20(15-29-24)25(33)28-3)12-13-32(17)22-8-10-30(11-9-22)18(2)19-4-6-21(26)7-5-19/h4-7,14-15,17-18,22H,8-13,16H2,1-3H3,(H,28,33)/t17-,18?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 |
Bioorg Med Chem Lett 21: 1527-31 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.114 BindingDB Entry DOI: 10.7270/Q2CZ37FJ |
More data for this Ligand-Target Pair | |