Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 447.5 BDBM50440713

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50440713 (CHEMBL2430977) Show SMILES CNc1cc(ccn1)-c1cc(NC(=O)[C@H](Cc2ccccc2)NCc2cncs2)n(C)n1 |r| Show InChI InChI=1S/C23H25N7OS/c1-24-21-11-17(8-9-26-21)19-12-22(30(2)29-19)28-23(31)20(10-16-6-4-3-5-7-16)27-14-18-13-25-15-32-18/h3-9,11-13,15,20,27H,10,14H2,1-2H3,(H,24,26)(H,28,31)/t20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...				ACS Med Chem Lett 4: 829-34 (2013) Article DOI: 10.1021/ml4000854 BindingDB Entry DOI: 10.7270/Q2JM2C20
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