Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor IX
(Homo sapiens (Human)) | BDBM183046
(US9150544, 80)Show SMILES COC(=O)[C@@H](Cc1cc2ccnc(N)c2cc1C(F)(F)F)N1CC[C@H](NS(=O)(=O)c2cnc(s2)N2CCCC2)C1=O |r| Show InChI InChI=1S/C25H27F3N6O5S2/c1-39-23(36)19(11-15-10-14-4-6-30-21(29)16(14)12-17(15)25(26,27)28)34-9-5-18(22(34)35)32-41(37,38)20-13-31-24(40-20)33-7-2-3-8-33/h4,6,10,12-13,18-19,32H,2-3,5,7-9,11H2,1H3,(H2,29,30)/t18-,19+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi
US Patent
| Assay Description
The compounds according to the invention are tested in a range of concentrations (4.9 nM to 5 µM final) and deposited in a proportion of 25 µl per we... |
US Patent US9150544 (2015)
BindingDB Entry DOI: 10.7270/Q27S7MKF |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM183046
(US9150544, 80)Show SMILES COC(=O)[C@@H](Cc1cc2ccnc(N)c2cc1C(F)(F)F)N1CC[C@H](NS(=O)(=O)c2cnc(s2)N2CCCC2)C1=O |r| Show InChI InChI=1S/C25H27F3N6O5S2/c1-39-23(36)19(11-15-10-14-4-6-30-21(29)16(14)12-17(15)25(26,27)28)34-9-5-18(22(34)35)32-41(37,38)20-13-31-24(40-20)33-7-2-3-8-33/h4,6,10,12-13,18-19,32H,2-3,5,7-9,11H2,1H3,(H2,29,30)/t18-,19+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.23E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Sanofi
US Patent
| Assay Description
The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ... |
US Patent US9150544 (2015)
BindingDB Entry DOI: 10.7270/Q27S7MKF |
More data for this
Ligand-Target Pair | |