Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor X
(Homo sapiens (Human)) | BDBM183051
(US9150544, 85)Show SMILES COC(=O)[C@@H](Cc1cc2ccnc(N)c2cc1Cl)N1CC[C@H](NS(=O)(=O)c2cnc(s2)N2CCC2)C1=O |r| Show InChI InChI=1S/C23H25ClN6O5S2/c1-35-22(32)18(10-14-9-13-3-5-26-20(25)15(13)11-16(14)24)30-8-4-17(21(30)31)28-37(33,34)19-12-27-23(36-19)29-6-2-7-29/h3,5,9,11-12,17-18,28H,2,4,6-8,10H2,1H3,(H2,25,26)/t17-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Sanofi
US Patent
| Assay Description
The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ... |
US Patent US9150544 (2015)
BindingDB Entry DOI: 10.7270/Q27S7MKF |
More data for this
Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM183051
(US9150544, 85)Show SMILES COC(=O)[C@@H](Cc1cc2ccnc(N)c2cc1Cl)N1CC[C@H](NS(=O)(=O)c2cnc(s2)N2CCC2)C1=O |r| Show InChI InChI=1S/C23H25ClN6O5S2/c1-35-22(32)18(10-14-9-13-3-5-26-20(25)15(13)11-16(14)24)30-8-4-17(21(30)31)28-37(33,34)19-12-27-23(36-19)29-6-2-7-29/h3,5,9,11-12,17-18,28H,2,4,6-8,10H2,1H3,(H2,25,26)/t17-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi
US Patent
| Assay Description
The compounds according to the invention are tested in a range of concentrations (4.9 nM to 5 µM final) and deposited in a proportion of 25 µl per we... |
US Patent US9150544 (2015)
BindingDB Entry DOI: 10.7270/Q27S7MKF |
More data for this
Ligand-Target Pair | |