Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 481.5 BDBM50494922

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50494922 (CHEMBL2437266) Show SMILES COC(=O)[C@@H](Cc1ccccc1)NC(=O)CC\C(C)=C\Cc1c(O)c2C(=O)OCc2c(C)c1OC |r| Show InChI InChI=1S/C27H31NO7/c1-16(10-12-19-24(30)23-20(15-35-27(23)32)17(2)25(19)33-3)11-13-22(29)28-21(26(31)34-4)14-18-8-6-5-7-9-18/h5-10,21,30H,11-15H2,1-4H3,(H,28,29)/b16-10+/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of IMPDH2 (unknown origin)				Bioorg Med Chem Lett 24: 332-6 (2014) Article DOI: 10.1016/j.bmcl.2013.11.005 BindingDB Entry DOI: 10.7270/Q2BP05RJ
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50494922 (CHEMBL2437266) Show SMILES COC(=O)[C@@H](Cc1ccccc1)NC(=O)CC\C(C)=C\Cc1c(O)c2C(=O)OCc2c(C)c1OC |r| Show InChI InChI=1S/C27H31NO7/c1-16(10-12-19-24(30)23-20(15-35-27(23)32)17(2)25(19)33-3)11-13-22(29)28-21(26(31)34-4)14-18-8-6-5-7-9-18/h5-10,21,30H,11-15H2,1-4H3,(H,28,29)/b16-10+/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of IMPDH1 (unknown origin)				Bioorg Med Chem Lett 24: 332-6 (2014) Article DOI: 10.1016/j.bmcl.2013.11.005 BindingDB Entry DOI: 10.7270/Q2BP05RJ
					More data for this Ligand-Target Pair