Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 266.2 BDBM24278

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24278 (Modified amino acid analog, 9a | methyl (2S)-2-ami...) Show SMILES COC(=O)[C@@H](N)CCC(=O)Nc1ccc(OC)cc1 |r| Show InChI InChI=1S/C13H18N2O4/c1-18-10-5-3-9(4-6-10)15-12(16)8-7-11(14)13(17)19-2/h3-6,11H,7-8,14H2,1-2H3,(H,15,16)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair