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Compile Data Set for Download or QSAR

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 315.3
BDBM50046340

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))
BDBM50046340
PNG
(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Show SMILES COC(=O)[C@@H](O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C18H21NO4/c1-22-18(21)17(20)16(19)11-13-7-9-15(10-8-13)23-12-14-5-3-2-4-6-14/h2-10,16-17,20H,11-12,19H2,1H3/t16-,17-/m0/s1
PDB
MMDB

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Similars

PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes


J Med Chem 36: 211-20 (1993)


BindingDB Entry DOI: 10.7270/Q2T152P3
More data for this
Ligand-Target Pair