Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM12818
(2,2,2-trifluoroacetic acid; methyl (1R,2S)-2-[2-(5...)Show SMILES COC(=O)[C@@H]1CCCC[C@@H]1NC(=O)C(Cc1ccccc1)c1csc2ccc(cc12)C(N)=N |r| Show InChI InChI=1S/C26H29N3O3S/c1-32-26(31)18-9-5-6-10-22(18)29-25(30)20(13-16-7-3-2-4-8-16)21-15-33-23-12-11-17(24(27)28)14-19(21)23/h2-4,7-8,11-12,14-15,18,20,22H,5-6,9-10,13H2,1H3,(H3,27,28)(H,29,30)/t18-,20?,22+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
| Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter... |
Bioorg Med Chem Lett 15: 29-35 (2005)
Article DOI: 10.1016/j.bmcl.2004.10.045 BindingDB Entry DOI: 10.7270/Q2K072H3 |
More data for this Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM12818
(2,2,2-trifluoroacetic acid; methyl (1R,2S)-2-[2-(5...)Show SMILES COC(=O)[C@@H]1CCCC[C@@H]1NC(=O)C(Cc1ccccc1)c1csc2ccc(cc12)C(N)=N |r| Show InChI InChI=1S/C26H29N3O3S/c1-32-26(31)18-9-5-6-10-22(18)29-25(30)20(13-16-7-3-2-4-8-16)21-15-33-23-12-11-17(24(27)28)14-19(21)23/h2-4,7-8,11-12,14-15,18,20,22H,5-6,9-10,13H2,1H3,(H3,27,28)(H,29,30)/t18-,20?,22+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
| Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter... |
Bioorg Med Chem Lett 15: 29-35 (2005)
Article DOI: 10.1016/j.bmcl.2004.10.045 BindingDB Entry DOI: 10.7270/Q2K072H3 |
More data for this Ligand-Target Pair | |