Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50210537
((S)-methyl 2-chloro-2-(2-((S)-2,6-dioxo-3-(3,4,5-t...)Show SMILES COC(=O)[C@](C)(Cl)NC(=O)CN1C(=O)CC[C@H](NC(=O)c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C21H26ClN3O9/c1-21(22,20(30)34-5)24-15(26)10-25-16(27)7-6-12(19(25)29)23-18(28)11-8-13(31-2)17(33-4)14(9-11)32-3/h8-9,12H,6-7,10H2,1-5H3,(H,23,28)(H,24,26)/t12-,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem Lett 17: 2935-8 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.095
BindingDB Entry DOI: 10.7270/Q2HT2P11 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50210537
((S)-methyl 2-chloro-2-(2-((S)-2,6-dioxo-3-(3,4,5-t...)Show SMILES COC(=O)[C@](C)(Cl)NC(=O)CN1C(=O)CC[C@H](NC(=O)c2cc(OC)c(OC)c(OC)c2)C1=O Show InChI InChI=1S/C21H26ClN3O9/c1-21(22,20(30)34-5)24-15(26)10-25-16(27)7-6-12(19(25)29)23-18(28)11-8-13(31-2)17(33-4)14(9-11)32-3/h8-9,12H,6-7,10H2,1-5H3,(H,23,28)(H,24,26)/t12-,21+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsomal aminopeptidase assessed as liberation of p-nitroanilide |
Bioorg Med Chem Lett 17: 2935-8 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.095
BindingDB Entry DOI: 10.7270/Q2HT2P11 |
More data for this
Ligand-Target Pair | |