Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50494945
(CHEMBL3098170)Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC\C(C)=C\Cc1c(O)c2C(=O)OCc2c(C)c1OC |r| Show InChI InChI=1S/C27H31NO8/c1-15(5-11-19-24(31)23-20(14-36-27(23)33)16(2)25(19)34-3)6-12-22(30)28-21(26(32)35-4)13-17-7-9-18(29)10-8-17/h5,7-10,21,29,31H,6,11-14H2,1-4H3,(H,28,30)/b15-5+/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 364 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description Inhibition of IMPDH2 (unknown origin) |
Bioorg Med Chem Lett 24: 332-6 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.005 BindingDB Entry DOI: 10.7270/Q2BP05RJ |
More data for this Ligand-Target Pair | |
Lanosterol synthase
(Homo sapiens (Human)) | BDBM50494945
(CHEMBL3098170)Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC\C(C)=C\Cc1c(O)c2C(=O)OCc2c(C)c1OC |r| Show InChI InChI=1S/C27H31NO8/c1-15(5-11-19-24(31)23-20(14-36-27(23)33)16(2)25(19)34-3)6-12-22(30)28-21(26(32)35-4)13-17-7-9-18(29)10-8-17/h5,7-10,21,29,31H,6,11-14H2,1-4H3,(H,28,30)/b15-5+/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description Inhibition of IMPDH1 (unknown origin) |
Bioorg Med Chem Lett 24: 332-6 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.005 BindingDB Entry DOI: 10.7270/Q2BP05RJ |
More data for this Ligand-Target Pair | |