Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 330.4 BDBM50042448

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50042448 (7-Formyl-6-methoxy-1,4a-dimethyl-1,2,3,4,4a,9,10,1...) Show SMILES COC(=O)C1(C)CCC[C@@]2(C)[C@H]1CCc1cc(C=O)c(OC)cc21 Show InChI InChI=1S/C20H26O4/c1-19-8-5-9-20(2,18(22)24-4)17(19)7-6-13-10-14(12-21)16(23-3)11-15(13)19/h10-12,17H,5-9H2,1-4H3/t17-,19-,20?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Effective concentration against DNA polymerase alpha				J Med Chem 36: 3503-10 (1994) BindingDB Entry DOI: 10.7270/Q2HT2PXP
					More data for this Ligand-Target Pair