Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 355.1 BDBM50318297

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50318297 (CHEMBL1094169 | Methyl (4R)-(2-Chloro-4-fluorophen...) Show SMILES COC(=O)C1=C(CCl)N=C(C)C(C#N)[C@H]1c1ccc(F)cc1Cl |r,c:4,t:8| Show InChI InChI=1S/C16H13Cl2FN2O2/c1-8-11(7-20)14(10-4-3-9(19)5-12(10)18)15(16(22)23-2)13(6-17)21-8/h3-5,11,14H,6H2,1-2H3/t11?,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act...				J Med Chem 53: 4300-4 (2010) Article DOI: 10.1021/jm1002827 BindingDB Entry DOI: 10.7270/Q22R3RV8
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