Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-lactamase TEM
(Escherichia coli) | BDBM178202
(US9120808, Example 32)Show SMILES COC(=O)C1N2[C@@H](CC2=O)OC1=C(CC=C)C(O)=O |w:11.12| Show InChI InChI=1S/C12H13NO6/c1-3-4-6(11(15)16)10-9(12(17)18-2)13-7(14)5-8(13)19-10/h3,8-9H,1,4-5H2,2H3,(H,15,16)/b10-6-/t8-,9?/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 122 | n/a | n/a | n/a | n/a | 7.0 | 37 |
NABRIVA THERAPEUTICS AG
US Patent
| Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ... |
US Patent US9120808 (2015)
BindingDB Entry DOI: 10.7270/Q2Q81BT5 |
More data for this Ligand-Target Pair | |
Beta-lactamase SHV-1
(Escherichia coli) | BDBM178202
(US9120808, Example 32)Show SMILES COC(=O)C1N2[C@@H](CC2=O)OC1=C(CC=C)C(O)=O |w:11.12| Show InChI InChI=1S/C12H13NO6/c1-3-4-6(11(15)16)10-9(12(17)18-2)13-7(14)5-8(13)19-10/h3,8-9H,1,4-5H2,2H3,(H,15,16)/b10-6-/t8-,9?/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 339 | n/a | n/a | n/a | n/a | 7.0 | 37 |
NABRIVA THERAPEUTICS AG
US Patent
| Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ... |
US Patent US9120808 (2015)
BindingDB Entry DOI: 10.7270/Q2Q81BT5 |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Escherichia coli) | BDBM178202
(US9120808, Example 32)Show SMILES COC(=O)C1N2[C@@H](CC2=O)OC1=C(CC=C)C(O)=O |w:11.12| Show InChI InChI=1S/C12H13NO6/c1-3-4-6(11(15)16)10-9(12(17)18-2)13-7(14)5-8(13)19-10/h3,8-9H,1,4-5H2,2H3,(H,15,16)/b10-6-/t8-,9?/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | 7.0 | 37 |
NABRIVA THERAPEUTICS AG
US Patent
| Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ... |
US Patent US9120808 (2015)
BindingDB Entry DOI: 10.7270/Q2Q81BT5 |
More data for this Ligand-Target Pair | |