Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 353.4 BDBM50121016

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50121016 (CHEMBL115170 | {1-[2-(4-Benzyl-phenoxy)-ethyl]-pyr...) Show SMILES COC(=O)CC1CCN(CCOc2ccc(Cc3ccccc3)cc2)C1 Show InChI InChI=1S/C22H27NO3/c1-25-22(24)16-20-11-12-23(17-20)13-14-26-21-9-7-19(8-10-21)15-18-5-3-2-4-6-18/h2-10,20H,11-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Inhibition of leukotriene A4 hydrolase in human recombinant assay				Bioorg Med Chem Lett 12: 3383-6 (2002) BindingDB Entry DOI: 10.7270/Q2N8795W
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