Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-V/beta-3
(Homo sapiens (Human)) | BDBM50141338
(2-(2-Carboxy-vinyl)-5-[3-(1,4,5,6-tetrahydro-pyrim...)Show SMILES COC(=O)c1cc(NC(=O)c2cccc(NC3=NCCCN3)c2)ccc1C=CC(O)=O |w:27.30,t:16| Show InChI InChI=1S/C22H22N4O5/c1-31-21(30)18-13-17(8-6-14(18)7-9-19(27)28)25-20(29)15-4-2-5-16(12-15)26-22-23-10-3-11-24-22/h2,4-9,12-13H,3,10-11H2,1H3,(H,25,29)(H,27,28)(H2,23,24,26) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA) |
Bioorg Med Chem Lett 14: 1471-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.015
BindingDB Entry DOI: 10.7270/Q2RJ4HXS |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50141338
(2-(2-Carboxy-vinyl)-5-[3-(1,4,5,6-tetrahydro-pyrim...)Show SMILES COC(=O)c1cc(NC(=O)c2cccc(NC3=NCCCN3)c2)ccc1C=CC(O)=O |w:27.30,t:16| Show InChI InChI=1S/C22H22N4O5/c1-31-21(30)18-13-17(8-6-14(18)7-9-19(27)28)25-20(29)15-4-2-5-16(12-15)26-22-23-10-3-11-24-22/h2,4-9,12-13H,3,10-11H2,1H3,(H,25,29)(H,27,28)(H2,23,24,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 817 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA) |
Bioorg Med Chem Lett 14: 1471-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.015
BindingDB Entry DOI: 10.7270/Q2RJ4HXS |
More data for this
Ligand-Target Pair | |