Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 451.2 BDBM409876

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM409876 (US10370333, Example IX-4) Show SMILES COC(=O)c1ccc2ncc(NS(=O)(=O)c3cc(Br)ccc3OC)cc2c1 Show InChI InChI=1S/C18H15BrN2O5S/c1-25-16-6-4-13(19)9-17(16)27(23,24)21-14-8-12-7-11(18(22)26-2)3-5-15(12)20-10-14/h3-10,21H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...				US Patent US10370333 (2019) BindingDB Entry DOI: 10.7270/Q2445PVM
					More data for this Ligand-Target Pair