Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 466.4 BDBM3204

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C eta type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM3204 ((+/-)-Methyl 2-[[2,6-dihydroxy-4-[[[3-(4-hydroxyph...) Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCCc1ccc(O)cc1 Show InChI InChI=1S/C25H22O9/c1-33-25(32)17-5-2-6-18(27)21(17)23(30)22-19(28)12-15(13-20(22)29)24(31)34-11-3-4-14-7-9-16(26)10-8-14/h2,5-10,12-13,26-29H,3-4,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.				J Med Chem 39: 5215-27 (1996) Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV
					More data for this Ligand-Target Pair