Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 558.6 BDBM435351

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435351 (US10568876, Example 112 | methyl 3-(2-(2-phenylace...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2CN(CCc12)C(=O)Cc1ccccc1 Show InChI InChI=1S/C36H34N2O4/c1-42-36(41)27-14-8-13-26(20-27)29-16-15-28(22-37-35(40)32-21-31(32)25-11-6-3-7-12-25)33-23-38(18-17-30(29)33)34(39)19-24-9-4-2-5-10-24/h2-16,20,31-32H,17-19,21-23H2,1H3,(H,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
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