Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 548.6 BDBM435333

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435333 (US10568876, Example 95 | methyl 3-(2-((1,5-dimethy...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2CN(Cc3ncn(C)c3C)CCc12 Show InChI InChI=1S/C34H36N4O3/c1-22-32(36-21-37(22)2)20-38-15-14-28-27(24-10-7-11-25(16-24)34(40)41-3)13-12-26(31(28)19-38)18-35-33(39)30-17-29(30)23-8-5-4-6-9-23/h4-13,16,21,29-30H,14-15,17-20H2,1-3H3,(H,35,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
					More data for this Ligand-Target Pair