Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 547.5 BDBM360348

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360348 (US9828369, Example 5 | methyl 3-(8-((1-(4-(trifluo...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CCN(CC2)c2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C31H28F3N3O3/c1-40-30(39)22-4-2-3-21(17-22)26-10-5-23(28-19-35-14-11-27(26)28)18-36-29(38)20-12-15-37(16-13-20)25-8-6-24(7-9-25)31(32,33)34/h2-11,14,17,19-20H,12-13,15-16,18H2,1H3,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair