Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH (unknown origin) at pH 9 |
Bioorg Med Chem Lett 18: 5847-50 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.086 BindingDB Entry DOI: 10.7270/Q2GF0TBV |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown |
J Med Chem 50: 1058-68 (2007)
Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Liver carboxylesterase 1
(Homo sapiens (Human)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of TGH |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50204485
(CHEMBL219880 | methyl 6-(2-(7-phenylheptanoyl)oxaz...)Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c1-28-23(27)19-14-9-13-18(25-19)21-16-24-22(29-21)20(26)15-8-3-2-5-10-17-11-6-4-7-12-17/h4,6-7,9,11-14,16H,2-3,5,8,10,15H2,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 hydrolase |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |