Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 407.4 BDBM50176673

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50176673 (2-methoxy-2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)et...) Show SMILES COC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO5/c1-15-21(25-23(30-15)16-6-4-3-5-7-16)12-13-29-18-9-11-19-17(14-18)8-10-20(19)22(28-2)24(26)27/h3-7,9,11,14,20,22H,8,10,12-13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Activity against PPAR alpha in human by FRET assay				Bioorg Med Chem Lett 16: 297-301 (2005) Article DOI: 10.1016/j.bmcl.2005.10.008 BindingDB Entry DOI: 10.7270/Q28P6025
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50176673 (2-methoxy-2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)et...) Show SMILES COC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO5/c1-15-21(25-23(30-15)16-6-4-3-5-7-16)12-13-29-18-9-11-19-17(14-18)8-10-20(19)22(28-2)24(26)27/h3-7,9,11,14,20,22H,8,10,12-13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by FRET assay				Bioorg Med Chem Lett 17: 4369-73 (2007) Article DOI: 10.1016/j.bmcl.2007.03.057 BindingDB Entry DOI: 10.7270/Q2GX4B8H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50176673 (2-methoxy-2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)et...) Show SMILES COC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO5/c1-15-21(25-23(30-15)16-6-4-3-5-7-16)12-13-29-18-9-11-19-17(14-18)8-10-20(19)22(28-2)24(26)27/h3-7,9,11,14,20,22H,8,10,12-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Agonist activity at GST-tagged human PPARdelta by FRET assay				Bioorg Med Chem Lett 17: 4369-73 (2007) Article DOI: 10.1016/j.bmcl.2007.03.057 BindingDB Entry DOI: 10.7270/Q2GX4B8H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50176673 (2-methoxy-2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)et...) Show SMILES COC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO5/c1-15-21(25-23(30-15)16-6-4-3-5-7-16)12-13-29-18-9-11-19-17(14-18)8-10-20(19)22(28-2)24(26)27/h3-7,9,11,14,20,22H,8,10,12-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Activity against PPAR gamma in human by FRET assay				Bioorg Med Chem Lett 16: 297-301 (2005) Article DOI: 10.1016/j.bmcl.2005.10.008 BindingDB Entry DOI: 10.7270/Q28P6025
					More data for this Ligand-Target Pair