Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 314.3 BDBM24293

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24293 ((4S)-4-amino-5-methoxy-N-(4-phenoxyphenyl)pentanam...) Show SMILES COC[C@@H](N)CCC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C18H22N2O3/c1-22-13-14(19)7-12-18(21)20-15-8-10-17(11-9-15)23-16-5-3-2-4-6-16/h2-6,8-11,14H,7,12-13,19H2,1H3,(H,20,21)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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