Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Renin
(Homo sapiens (Human)) | BDBM212499
(US10155731, Example 57 | US9278944, 57)Show SMILES COCCCn1nc(C)c2c(cc(cc12)[C@@H](C)N(C1CC1)C(=O)[C@H]1CNCCO1)C(F)(F)F |r| Show InChI InChI=1S/C23H31F3N4O3/c1-14-21-18(23(24,25)26)11-16(12-19(21)29(28-14)8-4-9-32-3)15(2)30(17-5-6-17)22(31)20-13-27-7-10-33-20/h11-12,15,17,20,27H,4-10,13H2,1-3H3/t15-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
MITSUBISHI TANABE PHARMA CORPORATION; SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
US Patent
| Assay Description
A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom... |
US Patent US10155731 (2018)
BindingDB Entry DOI: 10.7270/Q26M38WS |
More data for this
Ligand-Target Pair | |
Renin
(Homo sapiens (Human)) | BDBM212499
(US10155731, Example 57 | US9278944, 57)Show SMILES COCCCn1nc(C)c2c(cc(cc12)[C@@H](C)N(C1CC1)C(=O)[C@H]1CNCCO1)C(F)(F)F |r| Show InChI InChI=1S/C23H31F3N4O3/c1-14-21-18(23(24,25)26)11-16(12-19(21)29(28-14)8-4-9-32-3)15(2)30(17-5-6-17)22(31)20-13-27-7-10-33-20/h11-12,15,17,20,27H,4-10,13H2,1-3H3/t15-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
MITSUBISHI TANABE PHARMA CORPORATION; SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
US Patent
| Assay Description
A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome... |
US Patent US9278944 (2016)
BindingDB Entry DOI: 10.7270/Q20V8BMG |
More data for this
Ligand-Target Pair | |