Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 527.5 BDBM50211157

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50211157 ((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...) Show SMILES COCCN([C@H](C)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1)C(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H25F4N3O3/c1-18(34(15-16-38-2)25(36)17-19-7-9-20(10-8-19)28(30,31)32)26-33-24-6-4-3-5-23(24)27(37)35(26)22-13-11-21(29)12-14-22/h3-14,18H,15-17H2,1-2H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
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