Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 420.4 BDBM50210491

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210491 (CHEMBL399645 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES COCCNc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN6O/c1-29(2)15-16-9-12-30-20(14-16)28-21(17-4-6-18(24)7-5-17)22(30)19-8-10-25-23(27-19)26-11-13-31-3/h4-10,12,14H,11,13,15H2,1-3H3,(H,25,26,27)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair